Evaluating the potential carcinogenic hazard of glyphosate
نویسندگان
چکیده
منابع مشابه
Exposure to peroxisome proliferators: reassessment of the potential carcinogenic hazard.
Melnick (1) recently suggested that because peroxisome proliferation is not established as an obligatory step in the carcinogenicity of peroxisome proliferators (PPs), the proposal that the peroxisome proliferator di(2-ethylhexyl)phthalate (DEHP) poses no carcinogenic risk to humans (2) due to species differences in peroxisome proliferation should be viewed as an unvalidated hypothesis (1). In ...
متن کاملLetter: Potential hazard of tissue culture assays arising from carcinogenic compounds incompletely removed by washing.
[9J4C]N-2-Fluorenylacetamide and [6;~4C]3-methylchol anthrene were used to determine the percentage of labeled material removed at each stage of hamster embryo cell transformation assays. The repeated washings required by the procedures did not completely remove the labeled material from the cells and plastic dishes. It is recommended that dishes which have been exposed to chemical carcinogens ...
متن کاملEvaluation of carcinogenic potential of the herbicide glyphosate, drawing on tumor incidence data from fourteen chronic/carcinogenicity rodent studies
Abstract Glyphosate, an herbicidal derivative of the amino acid glycine, was introduced to agriculture in the 1970s. Glyphosate targets and blocks a plant metabolic pathway not found in animals, the shikimate pathway, required for the synthesis of aromatic amino acids in plants. After almost forty years of commercial use, and multiple regulatory approvals including toxicology evaluations, liter...
متن کاملReview of the carcinogenic potential of gasoline.
This review examines the animal, human, and mechanistic studies that precede the new studies reported in this volume. Wholly vaporized unleaded gasoline was found to produce a dose-dependent increase in renal carcinoma in male rats and an excess above background incidence of hepatocellular tumors in female mice in the high-dose group. Mechanistic studies suggest that gasoline is not mutagenic a...
متن کاملPotential Carcinogenic Risks of Aspartame
Aspartame is an intense artificial sweetener with a sweet test approximately 200 times that of sucrose and used as additive in more than 6,000 products. Aspartame was invented by GD-Searle in 1965 and submitted for pre-marketing safety evaluation in early 1980s. The studies conducted by GD-Searle to evaluate the potential carcinogenic risks of aspartame did not show any effect. Because of the g...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Critical Reviews in Toxicology
سال: 2016
ISSN: 1040-8444,1547-6898
DOI: 10.1080/10408444.2016.1234117